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There's anecdotal evidence that apple cider vinegar does help to repel mice. But the best way to repel mice is to keep your home scrupulously clean and seal up any obvious entry points. If you already have a mouse infestation, apple cider vinegar won’t get rid of the critters. It’s usually worth the cost of professional pest control to make sure a serious mouse problem is eradicated completely.

Nope, not typically, especially if a continuous food source is available. Rats will leave their nesting spots briefly to forage for food and water and then quickly return. The inherent danger of exposure keeps their departures short-lived. It's why resolving a minor infestation takes about three weeks, while a severe one can stretch to three months. Swift action is crucial to prevent rat populations from establishing a lasting presence.

Vinegar can be an insect repellant, as many bugs find its scent off-putting. However, vinegar is acidic and may also cause damage to any plants it comes in contact with. If you'd like to use vinegar to deter pests in your garden, be careful not to spray it directly on the plant's leaves or stems.

It's also worth noting that vinegar's effects can be short. To continue to repel bugs, you'll need to spray vinegar repeatedly. 

You can take multiple approaches to keep animals out of your edible landscape. You can use natural repellents such as mint and cayenne pepper to deter them from your garden. You can also build a fence (or opt for a privet hedge) or keep the most enticing plants in a sectioned-off area. The most efficient method of keeping your four-legged guests at bay is to determine what animal it is and create a customized plan for them.