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Squirrels hate not having access to secure shelter or food sources. Your best line of defense is to make your property less attractive by removing access to these things. There are chemical squirrel repellents, but these have mixed success. According to Pennsylvania State University, you can apply products containing the bittering agent denatonium saccharide to a squirrel's favorite fence, tree, or roof spots. However, you need to reapply repellents regularly, which aren’t scientifically proven effective.

Poison will kill small rodents and can seem like the quick and easy way to get rid of them. But—in addition to its inhumane nature—poison has some drawbacks. First of all, if you have small children or pets in the home, setting out poison isn't the best idea, as your pets or children could ingest it. 

Poisoned mice and rodents don't die instantly. Instead, it can take several days for the poison to work its way through their system. In the meantime, there's a chance that a predator, such as a cat, fox, or other mammal, will eat the poisoned rodent and become poisoned themselves.

Cockroaches are attracted to the smell of food. They're particularly attracted to grease, meat, cheese, sugar, and starch. Any rotten food such as fruits or vegetables puts off a strong odor that attracts the pests as well. Even dirty clothing can be enticing for cockroaches, which is why they're often found in laundry baskets.

No, you should never vacuum or sweep up mouse or rat droppings, as doing so can release harmful particles into the air and increase your risk of disease exposure. Instead, wear gloves and a mask, spray the droppings with a disinfectant spray, let it soak for a few minutes, and then carefully wipe them up with paper towels. Afterward, disinfect the area thoroughly and immediately wash your hands when you’re done.