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Pouring drain cleaner down a vent pipe isn’t recommended. First of all, unlike a clog in a sink or bath caused by such material as soap scum build-up, toothpaste, and hair, clogs in a vent pipe are likely the result of debris from trees or even an animal stuck in the pipe. Drain cleaners won’t be able to eat through this kind of material. The cleaner will only become clogged in the vent with the debris, causing even more problems.

In some cases, operating a snake can damage your drain and pipes. This depends on the overall condition of your pipes and how gently you operate the auger. For instance, older galvanized pipes covered in zinc are susceptible to scratches when using a drain snake. Additionally, it’s common for newbies to apply too much force when extending the snake, leading to scratches and related damage. You can also crack the porcelain with an electric auger if you’re snaking a toilet drain. If you’re using a manual snake or auger, the risk is minimal.

A bit of water in the bowl can help unclog a toilet, especially if you're using a plunger. However, if the bowl is full to the brim, you'll need to strap on gloves and remove some of the wastewater in a cup or container so it doesn't overflow when you try to unblock the pipe. If you're concerned about it filling further, manually close the flapper in the toilet tank or turn off the water supply to the toilet.

To unclog a plumbing vent, you first need to locate it. Look at your home's roofline. The plumbing vent will be a vertical pipe sticking straight up from the roof. Since this pipe runs all the way to the main drain underneath your house, you should also be able to find it in the attic.