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Bleach and freezing are your best bets here. The soft exoskeleton of spiders and spider eggs is no match to household bleach. Create a mixture that’s half water and half bleach and spray it directly onto the egg sac, and the spider eggs will be killed in less than five minutes. Freezing the egg sac or drowning it in cold water is another option.

To keep animals out, you must prevent them from entering. As long as they can get in, the problem will persist. That said, consider making your attic less inviting using deterrents like motion-activated lights or ultrasonic devices. Additionally, keeping a well-maintained, clean, and uncluttered attic that you regularly inspect for activity may make the space less attractive to critters.

Spiders are not typically attracted to bedding as a primary source of food or shelter, but they sometimes inadvertently end up there. Spiders can hitch a ride on your clothing, belongings, or through open windows and doors. The underside of a bed, especially if it's near a wall or corner, can provide such a sheltered spot where they can hide and build webs. Dust and clutter under your bed can create ideal hiding places as well. If your room has other insects like flies or mosquitoes, spiders may be drawn to the area in search of prey. 

You should not squish a roach because it can spread disease, attract more roaches, and release allergens. Roaches feed on the bodies of dead roaches, making more of them come. Squashing an individual roach only kills that one, whereas boric acid powder or baking soda can kill an entire population because it travels back to the nest before dying.