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To remove odor from a leather couch, let's focus first on what not to do.

A quick Google search may suggest using vinegar to do the job—don't. The acid will dry out anything made of leather. A better DIY option is to sprinkle a little baking soda on your sofa and let it rest for a few hours. Afterward, vacuum it up with a soft-attachment brush. You can also try airing your sofa by opening windows or leaving it outside for a few hours in a clean, dry space.

Stay away from using window cleaners and other harsh cleaning solutions on antique wood—or any wood in your home for that matter. The pH of the cleaners can break down the finish and permanently damage and stain the wood below. Even when it comes to more durable areas, such as when cleaning your baseboards, only use cleaning solutions that are safe for porous materials. 

Sometimes you will need a stronger cleaning solution to thoroughly clean furniture before painting. It’s best to start with a mild solution to avoid damaging the surface, especially if it is an antique piece. If you need to use a stronger mixture, try a commercial cleaner or mineral spirits. Before applying any solution, do a test patch on an inconspicuous area so you don’t risk damaging the finish.

Leaving pee on a mattress for an extended period of time will make it harder to remove the moisture, increase the likelihood of unappealing stains forming, and make the urine odor linger for a longer time. Ideally, you should start cleaning a urine-soaked mattress immediately. You can start by spraying a 1:1 solution of white distilled vinegar and water over the stain and then blotting it out. Then, sprinkle baking soda over the affected area, let it sit for 8 to 10 hours, and then vacuum it out. If the issue persists, you might need to dispose of your mattress and replace it.