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An active cleaning agent and a drain snake is the best way to clean a main sewer line. You can purchase a regular or enzyme drain cleaner or make a DIY drain cleaner with baking soda. Use your chosen solution at least once a month or as needed to keep your sewer line clear. 

As a preventative measure, hydro jetting should be done every one to two years. However, the best practice is to hydro jet your sewer line once per year. The ideal frequency depends on several factors, including the age and condition of your pipes, how prone they are to clogging, how often the sewer line is used, and the type of waste disposed of in the system. If you frequently experience clogs or are unsure, it's best to ask a licensed plumber for a recommendation specific to your plumbing system.

It can take anywhere from one month to a couple of years for tree roots to grow back in sewer lines. Tree roots can cause extreme havoc on your sewer lines, potentially cracking them and causing untreated wastewater to make its way into the groundwater. Have a landscaping pro remove trees and roots before installing your system, or call a pro to do it retroactively as soon as you can.

If methods like hot water or a plunger don’t work on your clogged drain, you can snake your drain to dislodge the plug. This can be a messy process, taking some physical effort and additional time over the other drain-clearing options. You can purchase a drain snake at a hardware store and choose from handheld options or those attached to a drill. Just work slowly, and be ready to call a plumber if you’re unable to reach the clog from your drain or P-trap.