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Bleach and freezing are your best bets here. The soft exoskeleton of spiders and spider eggs is no match to household bleach. Create a mixture that’s half water and half bleach and spray it directly onto the egg sac, and the spider eggs will be killed in less than five minutes. Freezing the egg sac or drowning it in cold water is another option.

Skunks like to forage for grubs in the soil, like worms and insects, but they are also tempted by trash and pet food bowls, so keeping these items out of sight may help keep skunks away. Skunks also like to set up a den in dark places, such as a crawl space or outbuilding.

Most spiders are harmless or do little more than the equivalent of a bee sting. Prevention is the best option for more serious cases. Keep spiders out of your home when possible. When you find spiders, a spider nest, or egg sac, remove it quickly before an inquisitive pet or child gets involved. When children are old enough, teach them to recognize the few dangerous species of spiders and avoid them to prevent getting bitten.

If you find bed bugs on your mattress, your first step is to put your sheets, pillowcases, pillows, and nearby linens into a trash bag and wash them in hot water. Then, vacuum your mattress and the rest of your bedroom, paying special attention to the mattress seams and crevices near your headboard. Next, use one (or more) of the solutions listed above to kill any live bugs, or call an exterminator for a professional treatment.