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Poison will kill small rodents and can seem like the quick and easy way to get rid of them. But—in addition to its inhumane nature—poison has some drawbacks. First of all, if you have small children or pets in the home, setting out poison isn't the best idea, as your pets or children could ingest it. 

Poisoned mice and rodents don't die instantly. Instead, it can take several days for the poison to work its way through their system. In the meantime, there's a chance that a predator, such as a cat, fox, or other mammal, will eat the poisoned rodent and become poisoned themselves.

While vinegar doesn’t get rid of spider webs that already exist, spraying a mixture of vinegar and water in areas where you’ve found webs before will deter spiders from rebuilding there. The acetic acid within vinegar can harm and kill spiders, so they’ll want to stay as far away from this strong-smelling substance as they can get. 

Mites hate dry conditions, extreme temperatures, and specific scents. Since they prefer humid environments, eliminating moisture inside your home can help kill them off. If you have essential oils at your disposal, you can use eucalyptus, rosemary, and clove to help get rid of and keep mites at bay.

To kill fruit flies outdoors, you'll want to make a homemade insecticide or find a plant-safe, nontoxic product. Fill a garden sprayer with your chosen solution and apply it on your plants and around the base of your home's exterior. Take care to limit your exposure to insecticides, as they can irritate skin and eyes. Always rinse garden fruits and vegetables before eating them.