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You should wait at least 24 hours for drywall mud to dry before sanding or applying another coat. However, the exact drying time depends on several factors, including the thickness of the application, room temperature, humidity, and the type of compound used. Thicker layers, or projects in high humidity, may require 48 hours or more. Lightweight compounds tend to dry faster than heavier, all-purpose ones. You'll know the mud is ready when it feels completely dry and firm to the touch and has changed to a consistent light color. Sanding too early can cause smudging or gouges, so patience is essential for a smooth finish.

Although they have similar applications, spackle and joint compound are not the same. Their primary differences lie in their composition, consistency, and ideal use cases.

Spackle is composed of gypsum and binding agents, making it thicker than joint compound. It dries quickly and is easy to sand, which makes it ideal for small wall repair projects like filling nail holes or patching minor damage.

Joint compound, also known as drywall mud, consists of limestone and gypsum. It is primarily used for large-scale projects, such as taping and finishing the seams on newly installed drywall. It tends to shrink more than spackle and can be more difficult to spread.

While both products can be used to fill small depressions and cracks, spackle cannot replace joint compound for taping and mudding new drywall. Conversely, you can often use joint compound for small patching jobs typically done with spackle.

If the holes in the plaster are small, you can fill them with layers of patching plaster until they’re filled. After it dries, you can sand the plaster and paint over it. If the hole is much larger, consider using bonding plaster first and then a layer of patching plaster, completing the process with sanding and a layer of paint.

Yes, if there is mold in your drywall mud and you then use it to build walls in your house—or if mold develops in your set drywall, like it can in hot and humid areas—it can lead to illness. Mold in your drywall (or other parts of your home) can make existing respiratory conditions or allergies worse, and the effect can be more intense for those who have existing health issues or compromised immune systems.