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Steam cleaning a couch should get rid of most smells, but there are some more potent smells that require a bit more work than steam cleaning. For instance, steam cleaning won’t likely get the smell of pee out of a couch. To remove urine odor from a couch, you’ll most likely need to use an enzymatic cleaner, which targets the smell and stain.

Ozone smoke removal uses an ozone generator to eliminate stubborn odors from sources like house fires, wildfires, or cigarette smoke. Ozone (O3) is a highly reactive and unstable gas that effectively neutralizes smoke odors through a process called oxidation. It 'donates' its extra oxygen molecule to the organic compounds causing the smell, altering their structure and eliminating the odor, with oxygen being the primary byproduct. This method can be effective on building materials and furniture. However, because improper use of an ozone generator can be dangerous to your health, this treatment is best left to a professional.

Focus on cleaning the air after you’ve finished cleaning surfaces. Use air purifiers, moving them as necessary from room to room. The air filters should be cleaned or replaced, depending on the type of filters you have. Clean the air ducts by yourself or by hiring a pro. Finally, open doors and windows to ensure the space is properly ventilated.

In some cases, yes, it’s safe to spray hydrogen peroxide on your mattress, but the solution can damage memory foam mattresses, so you should only use it on non-memory foam mattresses. If you have a standard spring mattress, you can mix hydrogen peroxide with cold water in a 1:1 ratio and spray that on your urine-soaked mattress. If you’re cleaning pee out of a memory foam mattress, swap out the hydrogen peroxide for white distilled vinegar, or call in a professional mattress cleaner to avoid doing damage to your mattress.