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You’ll want to locate all areas in your home that could be a potential entry point for mice, such as doors, windows, vents, baseboards, holes, and cracks in your home’s foundation. Don’t forget to check less-obvious areas like the attic, plumbing and sewers, and even the roof and gutters. If you check these spots and don’t find any signs of mice, consider hiring a pest control pro to dig deeper into potential hiding spots.

To kill fruit flies outdoors, you'll want to make a homemade insecticide or find a plant-safe, nontoxic product. Fill a garden sprayer with your chosen solution and apply it on your plants and around the base of your home's exterior. Take care to limit your exposure to insecticides, as they can irritate skin and eyes. Always rinse garden fruits and vegetables before eating them.

Spiders are not typically attracted to bedding as a primary source of food or shelter, but they sometimes inadvertently end up there. Spiders can hitch a ride on your clothing, belongings, or through open windows and doors. The underside of a bed, especially if it's near a wall or corner, can provide such a sheltered spot where they can hide and build webs. Dust and clutter under your bed can create ideal hiding places as well. If your room has other insects like flies or mosquitoes, spiders may be drawn to the area in search of prey. 

It’s difficult to be sure bed bugs are gone, especially with DIY methods. Any treatment you use should also include dedicated beg bug traps to pick up stragglers and help you monitor how many are left. It usually takes around three weeks to clean up remaining bed bugs and make sure they aren’t returning any time soon. Hiring a bed bug exterminator can decrease the amount of time it takes to remove these pests.