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This varies based on the circumstance. Chemical-based pest control baits and poisons are usually the most potent, but they are unsafe to use around children and pets, so they won’t be a fit for every household.

Safer alternatives, such as boric acid and food-grade diatomaceous earth, can work as well, though they should still stay out of reach. Aside from that, the best thing any DIY-er can do is make their place uninviting by sealing off entry points, eliminating clutter, and maintaining a clean home.

The best way to permanently get rid of skunks is by setting up deterrents around your property to keep skunks out. Get rid of skunks permanently by:

• Not leaving food or water outside

• Installing a motion-sensor sprinkler system

• Installing fencing that’s at least 3 feet high and a foot deep

• Adding motion-sensor lights in the yard

• Cleaning up brush, sticks, woodpiles, and leaves on your property so skunks can’t use the materials for a nest

• Seal up cracks and holes around your property to prevent skunks from building a den

• Placing fresh lemon peels around the perimeter of your home

There is no exact science here, due to the nature of nests and how mice raise their young, but a good place to start is to inspect the droppings. A single mouse poops a lot, leaving around 50 droppings in a single day, likely near a primary food source. If you find only sporadic droppings, you likely have a small infestation. If you spot large mounds of droppings, you are dealing with a big problem.

Ground moles are not typically dangerous. They're not known to carry rabies like many other wild animals, such as raccoons, skunks, and bats. And they don't typically bite humans, although it's possible if they feel threatened. If you do get bitten by a mole, it's best to see a physician to be safe, but most often, the bite will heal on its own unless it gets infected.