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If you are not at high risk of contracting disease and take proper safety precautions, it’s considered generally safe to clean mouse droppings on your own. Before handling any droppings, make sure to put on protective equipment such as plastic gloves and a face mask. Individuals who are immunocompromised, have medical conditions, and children should especially avoid exposure to mouse droppings. 

There’s little scientific evidence to suggest that homemade remedies to ward off wildlife are effective. But, often, when using them alongside other management techniques, it won’t do any harm to try. Suggestions include using urine-soaked kitty litter or sweat-soaked clothing items. Try applying them around your fence perimeters. Always read the instructions carefully for any commercially-bought repellents and opt for EPA-approved products. Multiple applications, especially after rain, are often necessary.

Luckily, skunks aren’t challenging to get rid of. You can try to remove them slowly by filling their den entryway loosely with newspaper. Many skunks notice their den is in jeopardy and take off on their own. You can also try making a homemade spray of jalapeno pepper, yellow onion, and cayenne pepper—believe it or not, skunks are sensitive to these smells, so if you spray this around the den or in hard-to-reach places around your property, most skunks will take the hint and leave. 

Some suggest mothballs as a deterrent for iguanas, but they are ineffective and harmful. Mothballs contain chemicals like naphthalene or paradichlorobenzene, which are toxic to humans and animals, including iguanas. The fumes can cause respiratory problems, skin irritation, and other health issues. Moreover, using mothballs outdoors is not recommended, as they contaminate soil and water sources.