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DIY animal removal is rarely a good idea and is not advised for many reasons. First, these types of animals can carry diseases and, therefore, pose a health risk to you, your family, and your pets if mishandled. Second, depending on your city or municipality, it may be illegal to remove or handle wildlife yourself. 

Sealing your home against these animals yourself is also a bad idea. Trapping an animal under your house will cause odor and insect problems when it passes away. 

When you spray a roach, the chemicals, usually a mix of neurotoxins like pyrethroids or pyrethrins, start affecting its nervous system almost immediately. It disrupts the roach’s nerve signals, causing paralysis and eventually death. You'll often see the roach twitch, flip over on its back, and stop moving within seconds to minutes.

Squirrels are pretty skittish creatures, and they dread the presence of rodent-chasing dogs and cats. Sudden noises and bursts of activity can send them scampering away. Anything with an element of surprise, like motion-detecting lighting, strobe lights, and noisy wind chimes, can unsettle them. Even loud radios and voices can be perceived as threatening and terrifying to these furry critters.

Simply put,  there are much better approaches than using mothballs. Mothballs contain chemicals that can easily permeate a frog's delicate skin, leading to health problems. But it's not limited to just frogs; other animals and the environment could also face negative impacts. The US Environmental Protection Agency (EPA) has taken action. It emphasizes the importance of adhering to label instructions for products like this and not moving forward with off-label use.