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To maintain your mattress and keep it fresh, you should aim for a deep clean at least twice a year. However, if you have allergies, pets, or sweat heavily at night, you may want to clean it more frequently, such as every three to four months. In between deep cleanings, it's a good practice to vacuum the mattress surface regularly and spot-clean any stains as they occur. Using a mattress protector can significantly help by minimizing the buildup of allergens, dust mites, and bodily fluids, which can make your cleaning routine more effective. Remember to launder the protector regularly, as some dirt and sweat can still get through to the mattress.

Focus on cleaning the air after you’ve finished cleaning surfaces. Use air purifiers, moving them as necessary from room to room. The air filters should be cleaned or replaced, depending on the type of filters you have. Clean the air ducts by yourself or by hiring a pro. Finally, open doors and windows to ensure the space is properly ventilated.

Do not mix bleach with vinegar, ammonia, acidic liquids, or other cleaners or detergents as toxic fumes result from the chemical reaction. Mix bleach only with water to avoid dangerous chemical reactions. Even mixed with water to dilute it, bleach can still be harmful to your skin, eyes, and lungs.

The best solution for mopping floors depends on the type of floor you have, but a good all-around or multi-purpose DIY floor cleaner is 2 cups of warm water, 5 to 10 drops of liquid dish soap, and 1 tablespoon of lemon juice. This is safe to use on tile, laminate, wood, polished concrete, vinyl, and more, as it’s relatively neutral and lacks caustic and abrasive chemicals that could be harmful to children and pets. You can also use a multi-purpose commercial cleaner, but make sure to follow the directions for safety.