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According to the U.S. Environmental Protection Agency, pyrethrins and pyrethroids are the most common chemical compounds used to get rid of bed bugs. These chemicals force bed bugs out of their hiding spots and kill them on the spot so they are eliminated for good. Only professional exterminators can apply these treatments, and they are reserved for severe infestations.

Mice are very unlikely to go away on their own. As long as there is food and shelter available in your home, they’ll call it their home, too. If your DIY efforts aren’t working, you need to hire a local pest control service to remove the mice infestation. Aside from carrying diseases, mice can chew through wires, insulation, drywall, and more.

Skunks are nocturnal creatures, meaning they are primarily active at night, particularly around dusk and dawn. Their activity levels increase as the weather warms up, and they are generally dormant or inactive during the winter. Skunks are especially active during the spring months when they are foraging for fresh food and seeking mates. While they are typically not seen during the day, daytime activity is possible if a skunk is having trouble finding food, has babies to care for, or is severely ill.

Generally, squirrels are not considered aggressive toward humans. They are more likely to flee than confront people. However, like many animals, they may exhibit aggressive behavior if they feel threatened or cornered. If you approach a squirrel too closely or try to handle it, especially if it's a mother protecting her young, it may resort to defensive tactics such as biting or scratching.