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Pouring drain cleaner down a vent pipe isn’t recommended. First of all, unlike a clog in a sink or bath caused by such material as soap scum build-up, toothpaste, and hair, clogs in a vent pipe are likely the result of debris from trees or even an animal stuck in the pipe. Drain cleaners won’t be able to eat through this kind of material. The cleaner will only become clogged in the vent with the debris, causing even more problems.

You should hire a sewer service professional to unclog a main sewer line with tree roots. Tree roots can grow into the main sewer line, and this problem requires a specialized hydro jet, or rooter, that is powerful enough to clear the roots. The tree can also damage the main sewer line, and a professional will need to make repairs or replace the damaged sections. Sewer line replacement costs about $60 to $250 per linear foot.

No, you should avoid using liquid drain cleaners. These chemicals, often packed with sulfuric or hydrochloric acid, can wreak havoc on your pipes, causing erosion and potential leaks. They’re also dangerous to your health. If you’re dealing with a stubborn clog, manual removal or a professional plumber is your best bet. Chemical drain cleaners can often make things worse, especially if the clog stays put and the chemicals linger in your pipes.

In most areas, drain cleaning professionals don’t technically need a license, as they aren’t altering your plumbing system in any way. However, we recommend hiring a drain cleaning professional with a plumbing license and certification. Certified plumbers are more likely to provide professional solutions to drain clogs without damaging your system. They’ll also have the diagnostic tools and experience necessary to remove the clog entirely rather than providing a temporary solution, as a handyperson might. Use Angi’s state licensing tool to check your plumber’s professional licenses before hiring.