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This varies based on the circumstance. Chemical-based pest control baits and poisons are usually the most potent, but they are unsafe to use around children and pets, so they won’t be a fit for every household.

Safer alternatives, such as boric acid and food-grade diatomaceous earth, can work as well, though they should still stay out of reach. Aside from that, the best thing any DIY-er can do is make their place uninviting by sealing off entry points, eliminating clutter, and maintaining a clean home.

Squirrels rely heavily on their sense of smell and are deterred by a variety of scents. Some of the most effective smells for repelling them include peppermint oil, coffee grounds, white vinegar, garlic, cinnamon, rosemary, and predator urine. They also have a strong aversion to capsaicin, the compound that makes chili peppers hot, making capsaicin-based sprays an effective repellent for areas like gardens or bird feeders. For a DIY solution, you can create a spray from garlic and vinegar and apply it daily. Additionally, squirrels dislike strong, fresh scents, so placing items like strong-smelling soaps or dryer sheets in areas they frequent can also help keep them away.

Regular cleaning, proper food storage, sealing entry points, and professional inspections help prevent infestations.

There’s little scientific evidence to suggest that homemade remedies to ward off wildlife are effective. But, often, when using them alongside other management techniques, it won’t do any harm to try. Suggestions include using urine-soaked kitty litter or sweat-soaked clothing items. Try applying them around your fence perimeters. Always read the instructions carefully for any commercially-bought repellents and opt for EPA-approved products. Multiple applications, especially after rain, are often necessary.