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No, poison isn’t the best way to deal with animals in your attic. It’s unlikely to completely eradicate the problem, especially if you don’t take care of access points. Also, poisoned animals may die and decay in the attic, causing noxious odors. 

Some animals may leave the attic before the poison kills them, which could lead to nearby pets or other wildlife eating the animals and becoming poisoned themselves. Ultimately, it’s better to avoid using poison and contact a professional instead.

Luckily, skunks aren’t challenging to get rid of. You can try to remove them slowly by filling their den entryway loosely with newspaper. Many skunks notice their den is in jeopardy and take off on their own. You can also try making a homemade spray of jalapeno pepper, yellow onion, and cayenne pepper—believe it or not, skunks are sensitive to these smells, so if you spray this around the den or in hard-to-reach places around your property, most skunks will take the hint and leave. 

Although it would make things easier for you, animals won’t likely leave the attic on their own. Unless the animal finds seasonal respite in your attic, it’s likely to stay in a protected space as long as it is allowed. Get rid of animals in your attic by calling the appropriate wildlife removal professionals so they can safely and efficiently remove the critters from your home, being careful to avoid further damage to your home.

Groundhogs have a strong aversion to powerful scents, including garlic, ammonia, vinegar, hot peppers like cayenne, and predator urine. Various herbs such as rosemary, lavender, basil, mint, sage, thyme, and oregano can also act as deterrents. You can strategically use these odors around your property by planting these crops near your garden and by the entrances to groundhog burrows. Commercially available repellents offer another option, and for best results, scent-based deterrents should be used alongside other preventive measures.