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Ultimately, pulling weeds vs. spraying them depends on what’s happening in your yard and your personal preferences. Manual weed removal doesn’t introduce any chemicals into your landscape, targets specific problematic plants, produces immediate results, can be free if you go the DIY route, and is inexpensive with a weed service if you only have a handful of weeds. On the other hand, spraying is often preferable for severe weed infestations and situations involving difficult-to-pull weeds because it treats multiple weeds at once, is usually more effective long-term, is less time-consuming, and costs less when done by a pro.

Whether a one-time spray treatment to control mosquitoes is enough depends on multiple factors. Often, you’ll notice a big difference after one application. However, mosquitoes are likely to return if you don't reduce attractive standing water habitats. This usually takes four to eight weeks if it’s still prime mosquito season.

Mowing your grass regularly, especially if you’re mowing close to the ground, can help kill Johnsongrass. Frequent mowing helps limit the spread of Johnsongrass and can even deplete carbohydrate reserves in rhizomes over time. The more time you leave in between mowing, the more likely Johnsongrass is to regrow and take over your lawn. 

No, it's not really possible to completely prevent weed growth. Weeds are incredibly resilient—all they usually need is a tiny bit of dirt to sprout, so their eventual appearance is pretty much inevitable. However, you can definitely keep them at bay by getting rid of weeds as soon as you notice them. The longer you let them sit and grow roots, the more they'll spread.