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Drywall can be toxic to the environment and to humans in some cases. As drywall breaks down in a landfill and comes in contact with other organic chemicals, it can create hydrogen sulfide gas or leach into the groundwater. Additionally, the CDC recommends methods for controlling the inhalation of drywall dust when handled. While the common ingredients of drywall—gypsum, silica, and mica—are naturally occurring, they can cause irritation in some humans.

Plastering and skimming are two different techniques for finishing walls. Plastering involves applying a thick layer of a plaster mixture—typically containing gypsum, lime, cement, sand, and water—to create a new surface. This process often requires multiple coats and is used for repairing significant damage or creating decorative textures. Skimming, on the other hand, is a technique that involves applying a thin layer of drywall compound or joint compound over an existing surface to smooth it out, covering minor imperfections, small cracks, or uneven textures for a polished look. Plastering is generally more costly and labor-intensive than skimming. Although some people use the terms interchangeably, they refer to different processes and materials.

You should stagger drywall sheets to help prevent cracking. The joints between drywall sheets are the weak spots, so if you install drywall with seams aligned, you’ll create weak lines that run across the length of the wall and extend from floor to ceiling. But when you stagger drywall, the solid sections of panels will support the joints. This can prevent seams from cracking or separating due to fluctuating temperature and humidity, vibrations from movement inside the home, and gravity.

In framing, studs are placed at 16-inch intervals to coincide with the typical spacing of wall materials such as drywall or plywood. This spacing is called "on-center" and is necessary for maintaining structural stability and efficient use of materials. The 16-inch spacing also helps to distribute the weight evenly across the building's structure. For those looking to cut material costs and improve energy efficiency, 24-inch stud spacing can be employed through a method called "advanced framing". This requires careful planning and adherence to local building codes to ensure structural integrity.