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Bleach and freezing are your best bets here. The soft exoskeleton of spiders and spider eggs is no match to household bleach. Create a mixture that’s half water and half bleach and spray it directly onto the egg sac, and the spider eggs will be killed in less than five minutes. Freezing the egg sac or drowning it in cold water is another option.

Both spikes and loose nets can be installed over nest sites to prevent the bird from returning, but nets are not a humane option since birds and other wildlife can get tangled in them. 

Spikes are a humane alternative that deter nesting without harming the birds. In small areas, like vents, a very fine mesh net can be installed to prevent the bird from returning. These nets don't generally pose a risk to the birds.

Most treatments take 1-3 hours, but severe infestations may require multiple visits.

Effective methods include topical treatments, oral medications, fogging, and insect growth regulators. Professional pest control guarantees comprehensive results.