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There are several ways to kill poison ivy permanently. The trick is to keep it from coming back. Herbicides and natural remedies are highly effective for killing existing poison ivy plants. However, plant and root parts left behind can easily create new sprouts that turn into full-grown plants. The only way to permanently get rid of poison ivy is to be patient and diligent until all traces of the plant are dead and gone.

If you have a lot of tree roots in your yard or have experienced issues in the past, you should use tree root killer every six months to prevent roots from infiltrating your pipes. If you have an active invasion and aren’t seeing results, check the instructions on the bottle to see how often you can use it in a short period of mine.

Poison oak is similar to poison ivy in that it's in the same family of plants. Poison oak is identifiable by its rounded-off leaves and hairy leaf texture. Tree-climbing varieties live primarily in western states while low-growing poison oak bushes occupy the eastern states. Treat poison oak like poison ivy to get rid of it permanently.

Ultimately, pulling weeds vs. spraying them depends on what’s happening in your yard and your personal preferences. Manual weed removal doesn’t introduce any chemicals into your landscape, targets specific problematic plants, produces immediate results, can be free if you go the DIY route, and is inexpensive with a weed service if you only have a handful of weeds. On the other hand, spraying is often preferable for severe weed infestations and situations involving difficult-to-pull weeds because it treats multiple weeds at once, is usually more effective long-term, is less time-consuming, and costs less when done by a pro.