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You should add 1 to 4 inches of mulch, depending on your garden type and needs. Keep in mind that no amount of mulch can completely prevent weeds, but a heavier coverage (closer to 4 inches) can suppress weeds enough that you are only seeing them sprout every few weeks. Finer mulch prevents weeds more effectively than large mulch, so if you’re using mulched leaves or shredded bark, 1 to 2 inches will likely suffice, while 3 to 4 inches is best for larger mulch, like bark chips or straw.

There are many options to eradicate weeds right down to the roots. Vinegar works, but it takes a week or so to do its thing, and the same goes for many commercially available herbicides. Boiled water is a quick way to kill off roots, or you can pull up weeds at the root.

Buffalo grass is not a dense grass, so weeds can grow between the buffalo grass plants. However, as long as you don’t overwater your lawn, weeds have a hard time growing. If you do notice weeds, you can use granular herbicides that are safe for buffalo grass in early and late summer.

Technically, dandelions aren’t bad for your lawn, and they don’t directly kill grass. In fact, they appear in areas that are nutrient-deprived, and their long taproots can loosen the soil and bring nutrients closer to the surface. 

However, dandelions do spread quickly, and they can take over your lawn, eventually crowding out grass. This is why a healthy lawn is the best defense against dandelions.