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Buffalo grass is not a dense grass, so weeds can grow between the buffalo grass plants. However, as long as you don’t overwater your lawn, weeds have a hard time growing. If you do notice weeds, you can use granular herbicides that are safe for buffalo grass in early and late summer.

Johnsongrass and crabgrass are invasive weeds that can overtake your lawn. Crabgrass is a low-growing grass most often seen in lawns, flower beds, and vegetable gardens. While you may find Johnsongrass growing in your lawn, it will also grow in pastures, crop fields, and the edge of the road. Johnsongrass is much coarser than crabgrass. If left alone, Johnsongrass can grow up to 8 feet tall. 

Very carefully. You should be cautious when using any of the above methods, as any one of them could lead to you accidentally killing desired grasses and plants. However, there are selective herbicides that can target certain plants over others. Look for a product that only affects the type of weeds you want to eliminate and spares the plants you want to keep.

There are organic herbicide options that will kill grass but not flowers, including white vinegar or a dish soap solution. Commercial selective herbicides can also target grass over other plants, but read the instructions carefully to avoid damaging your garden. Herbicides that kill grass but not flowers usually include ingredients like clethodim and sethoxydim. Otherwise, your best bet will be to weed by hand.