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There are several ways to kill poison ivy permanently. The trick is to keep it from coming back. Herbicides and natural remedies are highly effective for killing existing poison ivy plants. However, plant and root parts left behind can easily create new sprouts that turn into full-grown plants. The only way to permanently get rid of poison ivy is to be patient and diligent until all traces of the plant are dead and gone.

Herbicide application, manual removal, and landscape fabric are common approaches.

Landscaping fabric can only help to prevent weed growth in the short term. It's not an ideal long-term solution because dirt will eventually make its way on top of it, causing weeds to sprout. These fabrics can also leave microplastics in the environment for many, many years, so pulling weeds using one of the methods in this guide as soon as you see them is a better long-term prevention strategy.