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Although they have similar applications, spackle and joint compound are not the same. Their primary differences lie in their composition, consistency, and ideal use cases.

Spackle is composed of gypsum and binding agents, making it thicker than joint compound. It dries quickly and is easy to sand, which makes it ideal for small wall repair projects like filling nail holes or patching minor damage.

Joint compound, also known as drywall mud, consists of limestone and gypsum. It is primarily used for large-scale projects, such as taping and finishing the seams on newly installed drywall. It tends to shrink more than spackle and can be more difficult to spread.

While both products can be used to fill small depressions and cracks, spackle cannot replace joint compound for taping and mudding new drywall. Conversely, you can often use joint compound for small patching jobs typically done with spackle.

Drywall can be toxic to the environment and to humans in some cases. As drywall breaks down in a landfill and comes in contact with other organic chemicals, it can create hydrogen sulfide gas or leach into the groundwater. Additionally, the CDC recommends methods for controlling the inhalation of drywall dust when handled. While the common ingredients of drywall—gypsum, silica, and mica—are naturally occurring, they can cause irritation in some humans.

Plaster provides a durable, soundproof, and moisture-resistant finish compared to drywall.

You can plaster over regular drywall, but it's essential to prepare the surface properly. Before plastering, the drywall should be clean, free of dust, and any loose or peeling paint should be removed. Applying a primer specifically designed for plastering can improve adhesion. Some professionals recommend applying a base coat of plaster or joint compound to create a better surface for the plaster to adhere to. Proper preparation ensures a smooth and durable plaster finish over regular drywall.