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There is conflicting advice on whether to leave a baking soda and vinegar mixture in a drain overnight. Some sources suggest it can be effective for tough clogs, recommending that you flush the drain with warm water in the morning as part of a monthly cleaning routine. However, other experts advise against leaving the mixture in for extended periods, as its caustic nature could corrode drainpipes if used too often or left in for too long.

Professional tools include drain snakes, hydro jets, cameras for line inspection, and enzymatic or chemical cleaners for dissolution.

If your drain doesn’t have metal crosshairs or crossbars, you should use a tub drain extractor. These tools create a grip on the drain so you can turn it using a 1/2-inch ratchet drive, drain key, or wrench. Your drain may not have crosshairs if it's old and broken.

Your sewer line can get grimy quickly. To prevent sludge buildup in your sewer line, pour a mixture of 1/3 cup of vinegar and 1/3 cup of baking soda down each drain in your home once a month. After about 30 minutes, flush the drain with hot water.

Some plumbers recommend 3/4 cup of bleach instead to clean any germs and bacteria that may build up in your sewer line. But this won’t break down any active clogs, and it cannot be combined with vinegar, as the mixture will create a toxic, hazardous gas.