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*The Angi rating for Sewer Cleaning companies in Mexico, MO is a rating based on verified reviews from our community of homeowners who have used these pros to meet their Sewer Cleaning needs.

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Last update on June 14, 2026

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Sewer Cleaning questions, answered by experts

Main sewer lines can clog for several reasons. For example, if you regularly dump oil or grease down your drain, it could eventually block your line. Sometimes, tree roots can penetrate and grow inside old sewer pipes, creating a major blockage. Flushing bulky items (like paper towels, diapers, or baby wipes) can also clog your plumbing system.

Sometimes, the drain is just too clogged—thanks, stubborn hair and soap scum. In this case, you’ll need a more powerful drain cleaner than you can DIY safely at home. But this doesn’t mean you have to choose a traditional drain cleaner. 

You can find biodegradable drain cleaners at your local home improvement store or online for those drains that need a little more oomph. 

While on the hunt for a formidable drain cleaner, the best options are non-chemical clog solutions that combine enzymes and bacteria.

Most commercial liquid drain cleaners work in 15 to 30 minutes. Consult the label on the bottle for additional instructions or time suggestions to prevent damage to your drainpipes. Alternative solutions such as baking soda, salt, white vinegar, and/or boiling water can take longer since they are less harsh than liquid drain cleaners.

The average cost to snake your main sewer line is around $250 for a simple snake. Most sewer line specialists charge between $45 and $200 per hour for main sewer line snaking, so the time involved plays a major role. The price you’ll pay will depend on the severity of the clog, the item causing the backup, how long it takes to remove the item, and more. A more severe issue that requires unclogging a main sewer line will cost $3,100 on average.

It can take anywhere from half an hour to a few hours to fix a main line clog, depending on the cause and severity of it. The job should not take more than a day to complete. Keep in mind that the main line is not the same as your home’s sewer lines (which connect to the main line and run to your house). Your city is responsible for any clogs or damage to the main line itself.

The Mexico, MO homeowners’ guide to sewer cleaning services

From average costs to expert advice, get all the answers you need to get your job done.

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