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Yes, sewage smells can originate from a floor drain. If the P-Trap in the floor drain dries out or if there's a clog or other issue in the plumbing system, sewer gasses can escape through the drain, causing nasty odors. Regularly pouring water into the drain helps maintain the water seal and prevent those smells, but if the smell persists, you should have a plumbing professional inspect the drain for potential problems.

Knowing the signs can alert you to a clogged drain line. Clogs cause slow drainage or cause no drainage (if there’s a complete blockage). You may also notice foul odors, gurgling noises, water backing up in other appliances on the same line, or a poorly flushing toilet. If you experience any of these issues and think your line might be clogged, call a plumber.

To get rid of a sewer smell in your crawl space, you’ll have to find the source of the problem. If it has to do with your sewer lines, then repairing the line will help. You may need to make other repairs, like fixing your sump pump or encapsulating your crawl space to reduce moisture. After you make the repair, depending on the issue, you may still need to clean out your crawl space to get rid of the stink.

It is generally safe to stay in a house that smells like sewage for a short time, but you should get the problem fixed as soon as possible. While the level of sewer gas is usually low enough to only cause minor symptoms, prolonged inhalation can lead to headaches, nausea, or respiratory irritation. High levels of gas exposure can be more dangerous, and high concentrations of methane—a component of sewer gas—can pose an explosion risk in enclosed spaces. If you smell sewer gas in your home, ventilate the area and call a professional to locate, assess, and fix the problem, as it will not go away on its own.