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If you have a lot of tree roots in your yard or have experienced issues in the past, you should use tree root killer every six months to prevent roots from infiltrating your pipes. If you have an active invasion and aren’t seeing results, check the instructions on the bottle to see how often you can use it in a short period of mine.

If possible, you should prioritize pulling weeds up by hand. However, be sure not to use your bare hands, as many weeds are sharp or otherwise irritating when they come in contact with skin. Always don thick, protective gardening gloves to protect your hands when you pull up weeds.

Pulling weeds once per month is typically often enough to keep most weeds at bay. But in general, it's best to pull weeds as soon as you spot them to prevent deep root growth and slow their spread. To make it easier, plan your weed pulling after rain or after the sprinklers run so the soil will be nice and wet and the weeds will be easier to pull. If you notice moss accompanying weeds, make a plan to remove the moss immediately to prevent damage.

There are organic herbicide options that will kill grass but not flowers, including white vinegar or a dish soap solution. Commercial selective herbicides can also target grass over other plants, but read the instructions carefully to avoid damaging your garden. Herbicides that kill grass but not flowers usually include ingredients like clethodim and sethoxydim. Otherwise, your best bet will be to weed by hand.