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Luckily, skunks aren’t challenging to get rid of. You can try to remove them slowly by filling their den entryway loosely with newspaper. Many skunks notice their den is in jeopardy and take off on their own. You can also try making a homemade spray of jalapeno pepper, yellow onion, and cayenne pepper—believe it or not, skunks are sensitive to these smells, so if you spray this around the den or in hard-to-reach places around your property, most skunks will take the hint and leave. 

Squirrels hate not having access to secure shelter or food sources. Your best line of defense is to make your property less attractive by removing access to these things. There are chemical squirrel repellents, but these have mixed success. According to Pennsylvania State University, you can apply products containing the bittering agent denatonium saccharide to a squirrel's favorite fence, tree, or roof spots. However, you need to reapply repellents regularly, which aren’t scientifically proven effective.

Groundhogs are definitely cute, but it’s usually not a good idea to have them living in your yard. Not only can groundhogs tear up your grass and create unsightly holes and burrows, but they can also carry infectious diseases that are dangerous to humans.

Yes, dryer sheets can help repel mice. The strong artificial fragrances found in many dryer sheets, such as citrus, floral, or lavender, are unpleasant to mice, which are very sensitive to smells. Many people report success using them to deter mice from areas like cars, drawers, vents, and cupboards. The scent can last for many days, making the space undesirable for rodents. However, dryer sheets may not be a foolproof solution on their own. For more effective protection against rodent infestations, it is best to combine them with other preventive measures like traps, repellent sprays, and proper storage practices.