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A spot herbicide for weed control is effective at killing crabgrass and not grass, but it depends on the type of herbicide. Always check the label to ensure that your herbicide is safe for grass but tough on crabgrass. Overall, spot treatment is ideal because it puts fewer herbicides into the soil, which can damage the soil. If you’re wanting a natural remedy to crabgrass that also won’t harm surrounding grass, you can also hand-remove crabgrass or even pour boiling water or 5% vinegar over crabgrass as a spot treatment.

Several tools exist that can help remove unwanted grass. The one you choose depends greatly on how much you need to remove and how hard you'd like to work. A sod or turf cutter is the fastest method while using a shovel is labor-intensive and much slower. You may also need a garden rake, tiller, and wheelbarrow. 

Glyphosate and other non-selective herbicides can kill orchard grass, but they will also kill the surrounding plants. Also, not all areas allow the use of glyphosate due to its environmental impact—which the EPA describes as a "potential risk to terrestrial and aquatic plants and birds, and low toxicity to honeybees." Consider mechanical removal to target the plants specifically.

Adding vinegar to your lawn increases the acidity of the area, which can kill quack grass present above the ground. However, putting vinegar in your yard will also kill the grass. Unfortunately, the below-ground quack grass rhizomes remain very much alive in the presence of vinegar and will soon sprout again.