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You can use a homemade spray to kill fleas on a mattress. To make the spray, combine equal parts water and distilled white vinegar. Spray the mixture on the fleas and all over the mattress. Follow this up with a generous sprinkle of salt all over the mattress, and let it sit overnight. Finally, vacuum the mattress to clean up the salt, dead fleas, and flea offspring.

The signs of a bed bug infestation include itchy, red bite marks on the skin and various forms of physical evidence on or near your bed. Look for reddish or rust-colored stains on sheets from crushed bed bugs, as well as small, dark fecal droppings. You might also find the bugs themselves, their tiny eggs, or the pale, molted skins (casings) they leave behind. In some cases, a persistent musty odor may be present. If you notice any of these signs, calling a professional exterminator is the most effective way to handle the infestation.

A temperature of 131 degrees Fahrenheit for 72 minutes will kill bed bugs. Research suggests several different ranges, but many suggest starting at 120 degrees Fahrenheit and maintaining that heat for at least two hours. Steam cleaning is an exception because steam comes so hot it can quickly kill bed bugs and their eggs, making it a good option for fast extermination.

While it may seem counterintuitive, it is best to continue sleeping in your bed even if you have a bed bug infestation. If you move to another room, the bed bugs may follow you, which can spread the infestation to other parts of your home. To minimize bites while you sleep, wear protective clothing that covers as much of your body as possible, such as long-sleeved shirts, long pants, and socks. In the meantime, you should also isolate any potentially infested belongings and take steps to kill the bed bugs on your mattress as quickly as possible while waiting for professional treatment.