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Whether a one-time spray treatment to control mosquitoes is enough depends on multiple factors. Often, you’ll notice a big difference after one application. However, mosquitoes are likely to return if you don't reduce attractive standing water habitats. This usually takes four to eight weeks if it’s still prime mosquito season.

Buffalo grass is not a dense grass, so weeds can grow between the buffalo grass plants. However, as long as you don’t overwater your lawn, weeds have a hard time growing. If you do notice weeds, you can use granular herbicides that are safe for buffalo grass in early and late summer.

A spot herbicide for weed control is effective at killing crabgrass and not grass, but it depends on the type of herbicide. Always check the label to ensure that your herbicide is safe for grass but tough on crabgrass. Overall, spot treatment is ideal because it puts fewer herbicides into the soil, which can damage the soil. If you’re wanting a natural remedy to crabgrass that also won’t harm surrounding grass, you can also hand-remove crabgrass or even pour boiling water or 5% vinegar over crabgrass as a spot treatment.

Yellow patches, poor growth, or widespread weeds indicate a need for treatment. Soil testing can confirm nutritional deficiencies that require intervention.