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A two-way cleanout can help if there’s already a clog, but the best strategy to prevent one is by not rinsing grease, oil, or fat down your drains, not flushing or rinsing coffee grounds or egg shells down your drains, flushing only human waste and toilet paper (so no diapers, period products, bathroom wipes, or paper towels), and using drain guards on all of your drains.

Some flushable wipes companies say they are designed to disintegrate within a few hours to a few days after being flushed. These wipes allegedly use materials that are more water-soluble than traditional wipes. However, many experts have raised concerns that even so-called "flushable" wipes do not break down as easily as claimed and can contribute to clogs and blockages in sewer systems.

To prevent plumbing and sewer problems, avoid flushing wipes, even those labeled as flushable. Instead, dispose of them in the trash. This can help prevent costly plumbing issues and reduce the strain on wastewater treatment systems.

If the toilet is overflowing but there’s no clog, that’s a sign that the issue is deeper in the system, and plunging may not help. A blockage in your home’s plumbing, the plumbing vent, or even city sewer lines can cause toilets to overflow. The issue could also be the toilet itself if the filler float isn’t set to the correct height or if parts are damaged or worn out.

While not every clog has the same symptoms, the most common early sign that your main sewer line is clogged is that multiple drains in your home are draining slowly. You may also notice gurgling and odors from drains. If your plumbing system's drain cleanout is backing up with water, this is also a sign of a clog or blockage.