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No, it's not really possible to completely prevent weed growth. Weeds are incredibly resilient—all they usually need is a tiny bit of dirt to sprout, so their eventual appearance is pretty much inevitable. However, you can definitely keep them at bay by getting rid of weeds as soon as you notice them. The longer you let them sit and grow roots, the more they'll spread.

Weeds may grow back when pulled out if the root is not completely removed. Invasive weeds can regrow from just a small portion of remaining root, so using a weed-pulling tool can help ensure you remove the entire root. Weeds may grow back faster if roots aren’t fully removed, and incomplete removal could cause them to spread as well.

There are organic herbicide options that will kill grass but not flowers, including white vinegar or a dish soap solution. Commercial selective herbicides can also target grass over other plants, but read the instructions carefully to avoid damaging your garden. Herbicides that kill grass but not flowers usually include ingredients like clethodim and sethoxydim. Otherwise, your best bet will be to weed by hand.

Landscaping fabric can only help to prevent weed growth in the short term. It's not an ideal long-term solution because dirt will eventually make its way on top of it, causing weeds to sprout. These fabrics can also leave microplastics in the environment for many, many years, so pulling weeds using one of the methods in this guide as soon as you see them is a better long-term prevention strategy.