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A solution of one part bleach to 10 parts water or a disinfecting product that contains phenol (such as Lysol) is known to kill hantavirus and other pathogens found in mouse urine and feces. Simply spray this solution over and around the locations you expect mice to be living and running through, and the homemade disinfectant will do its job to rid your home of any feces and urine particles you could be exposed to.

Yes, it’s actually common to see more cockroaches after you spray. It might seem like things are getting worse, but that’s usually a sign the treatment is working. Roach sprays and baits can flush them out of their hiding spots as they try to escape the chemicals. You might notice them acting strangely—slower, twitching, or out during the day when they’re usually hiding.

Skunks spray as a defense mechanism to ward off predators. The active ingredient in their sulfurous, oily musk is n-butyl mercaptan, which evaporates into a powerful and smelly gas. Once the spray hits the skunk’s target, the stench can linger for days, and water and common cleaning kits aren’t enough to wash it away.

If you happen upon a skunk in your yard, try to back away slowly to reduce the chance of them aiming at you. Encouragingly, they don’t use their weapon casually, as it can take up to 10 days for their life-saving weaponry to refill. Paw stamping, hissing, lifting their tail, and arching their back are early signs they feel trapped or under threat and that it’s time to make a careful retreat.

In certain cases, yes, the bees may go away on their own, but it’s a risk. Some bee types, such as bumblebees, create seasonal nests and then die out as their new queens seek homes elsewhere. But in most cases, you can’t count on the bees leaving naturally. It’s also not a great idea to leave openings in your walls any longer than you have to, which can attract other pests or cause moisture damage.