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Most spiders are harmless or do little more than the equivalent of a bee sting. Prevention is the best option for more serious cases. Keep spiders out of your home when possible. When you find spiders, a spider nest, or egg sac, remove it quickly before an inquisitive pet or child gets involved. When children are old enough, teach them to recognize the few dangerous species of spiders and avoid them to prevent getting bitten.

Vinegar can be an insect repellant, as many bugs find its scent off-putting. However, vinegar is acidic and may also cause damage to any plants it comes in contact with. If you'd like to use vinegar to deter pests in your garden, be careful not to spray it directly on the plant's leaves or stems.

It's also worth noting that vinegar's effects can be short. To continue to repel bugs, you'll need to spray vinegar repeatedly. 

Both spikes and loose nets can be installed over nest sites to prevent the bird from returning, but nets are not a humane option since birds and other wildlife can get tangled in them. 

Spikes are a humane alternative that deter nesting without harming the birds. In small areas, like vents, a very fine mesh net can be installed to prevent the bird from returning. These nets don't generally pose a risk to the birds.

No, you should never vacuum or sweep up mouse or rat droppings, as doing so can release harmful particles into the air and increase your risk of disease exposure. Instead, wear gloves and a mask, spray the droppings with a disinfectant spray, let it soak for a few minutes, and then carefully wipe them up with paper towels. Afterward, disinfect the area thoroughly and immediately wash your hands when you’re done.