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You can easily find sprays that claim they are safe for pets and kids. However, we’d rather not use them in our own homes if we’re worried about pet safety: They still include pesticides and other chemicals, and are best avoided in any food prep areas like the kitchen, or any spots where children and pets may place. That’s why sprays didn’t end up in our suggestions for the safest options.

Squirrels follow a diurnal routine like humans, remaining quiet at night because they sleep. Homeowners concerned about squirrels in their homes are more likely to hear these critters in the early morning when they awaken, eager to start their day and search for sustenance. As the sun sets, squirrels wrap up their daily endeavors and return to their cozy nests for the night's rest.

It is very difficult to remove a colony entirely without using some kind of insecticide. However, some treatments are safer than others. Diatomaceous earth is a non-toxic powder application that creates barriers that insects can’t pass through. Some pest control companies offer liquid nitrogen treatments to freeze out termites without using pesticides. Some chemical treatments are safer to use around plants, water, and wildlife than others. Bait stations are generally less damaging to the environment than sprayed termiticides.

Wasps tend to be more aggressive and defensive than bees. Both will sting to defend themselves or their colony or nest. But many bees have barbed stingers, which means they can’t pull them out of the skin after stinging, allowing them to sting only once. When provoked, wasps can sting multiple times, making them a more menacing pest.