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Yes, vinegar can be an effective way to kill individual dandelion plants to help in the hand-removal process. However, vinegar can also kill turfgrass, so use a targeted spray.

Like sugar, the common household staple baking soda has uses in the yard. Baking soda boosts your plants to resist pests, fungal growth, and more. So, baking soda is good for your plants in certain instances, but exercise caution, as using too much could kill your plants. It’s great for hunting for pesky weeds, but not great for tending to a sensitive garden.

Noxious weeds can be poisonous or act as an irritant to humans, but not all are directly harmful. However, indirectly, noxious weeds also compete with native species, effectively affecting our local ecosystems of plants, pollinators, and other animals.

Glyphosate and other non-selective herbicides can kill orchard grass, but they will also kill the surrounding plants. Also, not all areas allow the use of glyphosate due to its environmental impact—which the EPA describes as a "potential risk to terrestrial and aquatic plants and birds, and low toxicity to honeybees." Consider mechanical removal to target the plants specifically.