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Skunks spray as a defense mechanism to ward off predators. The active ingredient in their sulfurous, oily musk is n-butyl mercaptan, which evaporates into a powerful and smelly gas. Once the spray hits the skunk’s target, the stench can linger for days, and water and common cleaning kits aren’t enough to wash it away.

If you happen upon a skunk in your yard, try to back away slowly to reduce the chance of them aiming at you. Encouragingly, they don’t use their weapon casually, as it can take up to 10 days for their life-saving weaponry to refill. Paw stamping, hissing, lifting their tail, and arching their back are early signs they feel trapped or under threat and that it’s time to make a careful retreat.

One of the best ways to get rid of mice is to prevent them from showing up in the first place with smart tricks—like placing a deterrent around the foundation of your house. Try building a barrier of rocks to make it harder for such rodents to get cozy in the small corners and crawl spaces that might give them access to the interior.

As a general rule, if you hear an animal in your attic, don’t assume it will stay there. Animals are drawn to warmth and food sources, which could lead them to other parts of your house. In particular, it’s likely that small pests such as rats and mice that only need tiny gaps to squeeze through will end up in your walls and ductwork. Larger animals like raccoons may be limited to an enclosed attic.

Luckily, spiders rarely “infest” a home like many other pests. They don’t tend to live in groups except when first born, and prefer their space. But you can prevent them from gaining entry by making sure your home is well-sealed and free of other insects. You can also lay down barrier sprays or powders designed to repel or kill spiders. Professionals can also lay down these barriers to prevent future spider problems.