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No, you should never vacuum or sweep up mouse or rat droppings, as doing so can release harmful particles into the air and increase your risk of disease exposure. Instead, wear gloves and a mask, spray the droppings with a disinfectant spray, let it soak for a few minutes, and then carefully wipe them up with paper towels. Afterward, disinfect the area thoroughly and immediately wash your hands when you’re done.

You should not squish a roach because it can spread disease, attract more roaches, and release allergens. Roaches feed on the bodies of dead roaches, making more of them come. Squashing an individual roach only kills that one, whereas boric acid powder or baking soda can kill an entire population because it travels back to the nest before dying.

The best way to ward off roaches is to take preventative measures and stay on top of routine extermination services. Keep them away by cleaning your kitchen free from crumbs, properly storing away food, covering your pet’s food bowl, and reducing moisture in your home to make your house less tempting for roaming cockroaches. Remove clutter—especially cardboard boxes that roaches love to hide in, and replace them with plastic tubs.

Most spiders are harmless and are more interested in finding and eating insects than trying to bite you or your family members. Certain spiders in your home may be advantageous if you have an issue with insects. Most spiders are non-venomous and have small mouths, so even if they did bite you, it wouldn’t be enough to cause any harm.

However, some species of spiders can cause harm if you are a victim of their spider bite, including the black widow and brown recluse varieties. Both species’ venom is poisonous, and you should seek medical help if bitten.