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Spiders are not typically attracted to bedding as a primary source of food or shelter, but they sometimes inadvertently end up there. Spiders can hitch a ride on your clothing, belongings, or through open windows and doors. The underside of a bed, especially if it's near a wall or corner, can provide such a sheltered spot where they can hide and build webs. Dust and clutter under your bed can create ideal hiding places as well. If your room has other insects like flies or mosquitoes, spiders may be drawn to the area in search of prey. 

DIY animal removal is rarely a good idea and is not advised for many reasons. First, these types of animals can carry diseases and, therefore, pose a health risk to you, your family, and your pets if mishandled. Second, depending on your city or municipality, it may be illegal to remove or handle wildlife yourself. 

Sealing your home against these animals yourself is also a bad idea. Trapping an animal under your house will cause odor and insect problems when it passes away. 

If you are not at high risk of contracting disease and take proper safety precautions, it’s considered generally safe to clean mouse droppings on your own. Before handling any droppings, make sure to put on protective equipment such as plastic gloves and a face mask. Individuals who are immunocompromised, have medical conditions, and children should especially avoid exposure to mouse droppings. 

Neither the black widow nor the brown recluse are deadly spiders, and North America has no deadly species. However, other places in the world do, including Australia, which is home to the funnel web spider, considered the world’s deadliest spider. However, Australia has not reported deaths from a funnel web spider bite over the past few decades after developing an antivenom.