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According to the Centers for Disease Control and Prevention (CDC), fleas can carry human disease-causing pathogens for Plague, Flea-borne typhus, and Cat scratch disease. These diseases are caused by fleas such as Oropsylla montana, Xenopsylla cheopis, and Ctenocephalides felis, and are commonly found in rural areas of the western United States, California, Texas, and Hawaii. Fleaborne parasites like tapeworms can also be spread to people and animals if they accidentally swallow an infected flea, and small children are at a higher risk. Symptoms may not be present in most infected people.

You should not spray pesticides of any kind into your air vents. The spray won’t reach far into the vent, minimizing its effectiveness in killing roaches, but more importantly, it’s dangerous for people and pets to inhale these chemicals. Roach spray is not a natural roach repellent, and it’s not safe to spray into air vents.

It’s debatable, but most will say either termites or bed bugs are the hardest to remove. When dealing with termites, you must find the central nest (as opposed to satellite nests) and exterminate the queen and all potential queens, which often takes the work of a specialist. Bed bugs, meanwhile, are incredibly hardy, good at hiding, and resistant to pesticides, so it takes very careful, very thorough work to get rid of them permanently. 

Gophers are ubiquitous in certain areas, and the only way to completely get rid of them is to put down gopher wire two feet below the surface of your soil and vertically along the edges of your yard. Unfortunately, this may not be a practical solution unless you’re completely redoing your yard or installing an aboveground garden. Alternatively, you may consider putting underground rock barriers around the edge of your yard to discourage gopher visits. However, you’ll still likely get some pests because they can dig as deep as 6 feet below the surface.