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If you try a drain snake and various DIY methods for unclogging drains to no avail, bring in a professional plumber to assess the situation. Also, if multiple drains in your home are backing up or you smell sewage, a visit from a plumber is best. You can expect your drain cleaning costs to fall around $250, and this can include an assessment of what’s caught in your plumbing and if there’s a larger, underlying problem. You should also consider calling a pro if you need to snake a toilet, as DIYing this could lead to a cracked fixture.

Start by pouring hot—but not boiling—water down the drain. The heat of the water may be enough to break down the clog. You can also try ½ cup of dish soap or 1 cup each of white vinegar and baking soda. If you choose a chemical unclogging product, ensure it’s appropriate for toilets to avoid damage.

Main sewer lines can clog for several reasons. For example, if you regularly dump oil or grease down your drain, it could eventually block your line. Sometimes, tree roots can penetrate and grow inside old sewer pipes, creating a major blockage. Flushing bulky items (like paper towels, diapers, or baby wipes) can also clog your plumbing system.

Never pour used motor oil down the drain. Doing so can have serious environmental consequences, including contaminating groundwater, endangering animals, and killing vegetation. It can also clog your pipes, causing backups in your plumbing or the wastewater treatment plant. In most places, pouring motor oil down the drain is illegal, whether you do it in your home or a storm drain.