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Once the animals and their young are out of the house, remove the nest and locate any entry points. Some may be difficult to find because some animals can fit through very small holes. Once you’ve located as many entry points as possible, use materials such as metal or masonry to block off the entry. Ideally, you should choose materials that most animals cannot chew through. Create a one-way door or flap to allow animals to leave but not return. Additional methods include using repellants designed to make an area unappealing to the types of animals that find your home so inviting. 

In some cases, a clean house can have roaches, especially if you have excess moisture somewhere. You may want to check for leaky pipes or look underneath sinks to make sure water isn’t dripping near a hidden area that is inviting the cockroaches in. Roaches can also take up residence in clean homes with not-protected food sources, like open bags of food in a kitchen cupboard.

Most spiders are harmless and are more interested in finding and eating insects than trying to bite you or your family members. Certain spiders in your home may be advantageous if you have an issue with insects. Most spiders are non-venomous and have small mouths, so even if they did bite you, it wouldn’t be enough to cause any harm.

However, some species of spiders can cause harm if you are a victim of their spider bite, including the black widow and brown recluse varieties. Both species’ venom is poisonous, and you should seek medical help if bitten.

Legal considerations include adherence to local and federal wildlife protection laws, particularly for species that might be protected or endangered.