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The difference between floor and wall tiles is that floor tiles generally have higher strength and porosity ratings than wall tiles. Wall tiles are typically weaker and more likely to crack or become damaged under sustained pressure like high foot traffic. 

For this reason, avoid using wall tiles on floors and vice versa.

Yes, but you should only put tile directly on drywall in smaller areas that don’t experience excess moisture. For example, a small kitchen tile backsplash could work, but installing tile directly on the drywall in a bathroom or other chronically damp area is not a good idea. Either way, a cement backer board is a far more reliable solution, as drywall is susceptible to moisture and can warp or cause your tiles to crack.

No, tiling over painted walls or wallpapered surfaces is generally not recommended. Textured surfaces and paints will affect the adhesive, possibly causing tiles to lift or fall off. Painted walls with a semi-gloss or high-gloss finish are particularly difficult for adding tiles. It’s wise to strip the paint first if you install the tiles to drywall, although it’s still best to opt for a cement backer board.

For best results, you should remove the toilet in a bathroom before removing tile or installing new tile. If you don’t remove the toilet, it will be harder to fully waterproof the tile around the toilet, which could increase the risk of mold growth or plumbing leaks. If you have trouble removing the toilet, hire a plumber to help.