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While keeping any critter away permanently isn’t always possible, you can keep mice away from your home by setting traps, fumigating your space, and sealing known entry points. Once you’ve taken these steps, take time to work on prevention measures, such as clearing out all clutter and recyclables and removing all food sources.

Fruit flies aren’t harmful by themselves, and they can’t bite or sting you. They can, however, spread bacteria around your home and can be a nuisance to live with. That’s why it’s important to eliminate fruit fly infestations quickly and enact preventative measures to keep them out of your house.

Poison will kill small rodents and can seem like the quick and easy way to get rid of them. But—in addition to its inhumane nature—poison has some drawbacks. First of all, if you have small children or pets in the home, setting out poison isn't the best idea, as your pets or children could ingest it. 

Poisoned mice and rodents don't die instantly. Instead, it can take several days for the poison to work its way through their system. In the meantime, there's a chance that a predator, such as a cat, fox, or other mammal, will eat the poisoned rodent and become poisoned themselves.

Tree sap is not usually dangerous to humans or pets. But some trees do produce dangerous sap. Notably, ash, birch, cedar and similar saps can irritate the skin but aren’t dangerous. Sap from trees like the Brazilwood, Mahogany, Milky Mangrove or well-named Poison Walnut can be corrosive, cause nausea, or trigger those with asthma. But for most backyard trees, protective equipment like a sturdy pair of gloves should be fine.