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If you are not at high risk of contracting disease and take proper safety precautions, it’s considered generally safe to clean mouse droppings on your own. Before handling any droppings, make sure to put on protective equipment such as plastic gloves and a face mask. Individuals who are immunocompromised, have medical conditions, and children should especially avoid exposure to mouse droppings. 

One way to keep pests away is with good housekeeping. Keep ants away with a clean kitchen. They’re less likely to wander in looking to score some free food if there isn’t a mess to find. Wipe down counters, don’t leave dirty dishes around, and keep food in air-tight containers. 

Home and yard maintenance can also keep pests away. Seal windows, patch any holes or cracks, and put screens on the vents to prevent bugs, rodents, and other uninvited guests from coming in.

Squirrels are pretty skittish creatures, and they dread the presence of rodent-chasing dogs and cats. Sudden noises and bursts of activity can send them scampering away. Anything with an element of surprise, like motion-detecting lighting, strobe lights, and noisy wind chimes, can unsettle them. Even loud radios and voices can be perceived as threatening and terrifying to these furry critters.

Both spikes and loose nets can be installed over nest sites to prevent the bird from returning, but nets are not a humane option since birds and other wildlife can get tangled in them. 

Spikes are a humane alternative that deter nesting without harming the birds. In small areas, like vents, a very fine mesh net can be installed to prevent the bird from returning. These nets don't generally pose a risk to the birds.