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In most cases, you should not use a pruning seal on trees after trimming. Applying a sealant can interfere with the tree's natural healing process, and it does not guarantee protection from pathogens. Instead of sealing the cut, the best practice is to support the tree's natural recovery by providing it with plenty of water and a dormant-style fertilizer. However, there are exceptions. Pruning seals may be recommended for very vulnerable species, like elm trees, in areas where dangerous diseases such as Dutch elm disease are prevalent. In these specific situations, the protection offered by a sealant can outweigh its downsides. For advice tailored to your situation, especially after cutting large branches, it is best to consult a local tree trimming professional.

Dutch elm disease can’t harm humans. In fact, according to Cal Fire, bark beetles aren’t even typically dangerous to trees unless that tree is already weakened. The problem comes when Dutch elm disease kills a tree. That tree is more at risk of falling and catching fire, which can pose a serious threat.

The best time to prune Japanese flowering cherry trees depends on where you live and the type of flowering cherry tree. Some trees benefit from being pruned toward the end of winter or early spring, after the last freeze. Meanwhile, other trees do well after blooming, in late spring or early summer. Avoid pruning your flowering cherry tree in the early winter, as this encourages open wounds that can lead to infections or infestations. 

No. Topping a tree refers to severely cutting down all its major branches and tree in a straight line. It was once recommended for streetside deciduous trees but has fallen out of practice. Topping leads to many problems, removing so much of the tree that many trees struggle to survive and become much more vulnerable to insects and diseases. Also, it doesn’t really help tree growth as once assumed and often leads to an ugly appearance of many sprouting stems in competition to become new main branches.